вЂњIn our sample, 18 participants with post-secondary education, including 9 college graduates, had abnormal scores on at least 1 cognitive test,вЂќ the authors said.ДЄdults with SCD experience hemolysis, inflammation, and vascular occlusion, which can cause end-organ injury. However, more than 60% of participants had a history of ACS operationalizing ACS differently, such as identifying those with ACS in the past 2 years, might have more predictive power,вЂќ the authors said.ДЄdditionally, patients with SCD with high educational attainment were found to be more vulnerable to deleterious cognitive disease processes. вЂњIn our sample, there was no significant association between history of ACS and cognitive performance. Prior history of ACS has not been previously explored in relation to cognitive performance, but these results suggest it might indicate increased disease severity.

The team also carried out a retrospective review of the participantsвЂ™ electronic medical records including acute chest syndrome (ACS). Both are validated tests of health literacy that have clinically meaningful cognitive domains modifiable by rehabilitation and mitigated by changes in clinical practice. Median MoCA scores were correlated with the validated Wide Range Achievement Test 4 and the Test of Functional Health Literacy in Adults. The purposes of the investigation were to detect whether MoCA scores correlate with literacy and health literacy levels in adults with SCD to identify clinical factors linked with poor performance on the MoCA, literacy, and health literacy assessments and to characterize the patients with high educational attainment who obtain abnormal cognitive testing scores. Researchers recently found that the Montreal Cognitive Assessment (MoCA) score is a promising option for screening cognitive impairment in adults with sickle cell disease (SCD) and published their findings in the British Journal of Haematology.Д®arly et al enrolled 49 adults with SCD who received care at the Johns Hopkins Sickle Cell Center for Adults in Baltimore, Maryland.

Moca cognitive assessment